Born Mae Kwestel within New York City, Questel win a talent contest at a age of Xvii, & began performing on vaudeville. She was seen by Max Fleischer who was looking for an actress to provide a voice for his Betty Boop character. Questel's "Boop-boop-a-doop" routine, neutralize the style similar thereto of the song's mastermind, Helen Kane, was exactly what Fleischer had been wanting to find. From either 1930 until 1939 Questel provided a voice of Betty Boop around further than 150 animated shorts. When you took the Thirties she freed a recording of "On The Good Ship Lollypop" which sold further than Two million copies.

From either a mid Thirties Questel as well provided a voice for Olive Oyl in the Popeye animated shorts. She depending Olive's rhinal vocal style thereon of the actress ZaSu Pitts, ultimately swimming a role for extra than twenty years.

She mass produced her foremost in-screen appearance in the 1960s, and wwhen widely seen as one of Fanny Brice's mother's card-playing friends inside Funny Girl (1968), and likewise appeared around Zelig (1983), New York Stories (1989) (making her the exclusively actress to ever play Woody Allen's mother on-screen), & her final film appearance around ''National Lampoon's Christmas Vacation (1989). She besides provided the voice for her old character Betty Boop world health organization mass produced a cameo appearance around Who Framed Roger Rabbit'' (1988). She appeared inside TV commercial message for various home products, becoming far-famed when "Aunt Bluebell" world health organization pitched ScotTowels.

Questel died from either Alzheimer's Disease at the age of 89 in New York City in 1998.